Thread: CoronaVirus ==> Empty Shelves

Originally Posted by BobL

Because of things like lack of openness/public accountability, insufficient testing, and the fact they are mostly early on in the game, any data from Africa, Central and South America, Asia (except for Singapore), Middle East, or Eastern Europe would have to be suss. In many of these places there's bugger all medical services and people already dying constantly for all sorts of reasons with not a medical person in sight let alone one that would be able to confirm a death as attributable to COVID19, so my guess is we'll never know what their real COVID19 death rates are. In the UK and the US additional people are dying in retirement homes and many of these are not being officially recorded as COVID19 deaths.

Doesn't really leave much of value to compare with does it?

We curse our systems and politicians, BUT on this one they've really done well.

Makes me glad to be living here.

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Now to fix the environment....

...and the best response I get is:


I went looking for the "Do Not Feed the Troll" smilie

Pathetic!

Originally Posted by Tccp123

Well I still don't know anyone with the virus, nor do I know anyone who knows anyone with it! That's not surprising because here in Queensland only one in 20,000 people that you're likely to run into on the streets has it. And then you have to catch it from them! Pretty good odds I think. I don't wear a mask, I don't possess any hand sanitizer, and I don't have the virus. If it wasn't for the heavy handed police presence (who appear to be immune to it) I'd be out there on the streets!

But what's the next move? I can't see any alternative to herd immunity but it would take a brave person to suggest we go down that route...

Fortunately we will soon be able to see how that works because Indonesia has no choice. There is no way they can enforce social distancing, they can't afford the testing (even if it was available), and they don't have the health system to support a catastrophe.

I understand where you are coming from but you could look at it this way. If we didn’t approach it like we have done your statement could well of been “I still don’t know anyone who hasn’t had the virus”

I get it about the impact on the economy but think it is a balancing act of keeping the economy running V an acceptable amount of infections that our healthcare system can manage. I think we need to accept there will be deaths and we need to maintain as normal a life as we can with a palatable death rate associated with it
I can’t see how it can go any other way unless there is a miracle cure

Originally Posted by Tccp123

Pretty good odds I think. I don't wear a mask, I don't possess any hand sanitizer, and I don't have the virus. If it wasn't for the heavy handed police presence (who appear to be immune to it) I'd be out there on the streets!

I'm still out on the streets without a mask, sanitiser or the virus. With all of the restrictions in place, the only difference to my life is that I kinda wanted to play poker at the casino on Easter Sunday, but I couldn't because it is shut. The blokes I have spoken to about this at work are in the same boat. Basically no change to any part of their lives. What I am saying is that the restrictions could be a whole lot worse.

Originally Posted by Tccp123

I can't see any alternative to herd immunity but it would take a brave person to suggest we go down that route...

When you mention herd immunity, does this mean "the ones that are left"?

I ask, as with immunisation, this is what I know H.I. as: "the vast % of the pop get the shot and the 1% who cant, for whatever reason, survive due to the social good of others."

If its the other way around, just letting the cull occur due to an individuals bad luck, a slight genetic difference that disadvantages some, or some other thing (such as ripping through the cities and passing the towns), then I don't think too much of "Herd Immunity" as a strategy.

So far, from what I know, only certain people have a genetic predisposition that seems to confer a slightly more favourable outcome.

I've also read that this foul beastie is now 3 discrete versions (on top of the dozens of minor variants)... so while one may be *immune* to a particular variant, the others will surely get ye!

This is one thing I'm leaving FIRMLY to the scientists.



Our only response, as good people, is to minimise damage/harm to those who cannot be protected and ensure everyone's treated fairly.

I'm seeing a lot of good in people over this. I am happy that people are being people again and deprogramming themselves of corporatism.

Here is an interesting read: Australians share great acts of kindness during the coronavirus crisis

Originally Posted by Tccp123

Well I still don't know anyone with the virus, nor do I know anyone who knows anyone with it!

Ah! I've news!

Yes, my neighbour definitely was a plague victim.

As best as I can tell, everything was moved out over the weekend. I'm not sure if he went off to the farm.... or simply back to mums to recover. No news there..... but, somewhat interestingly, the unit went up for rent about 10 days ago. This area, until the plague, had 20 groups to a viewing for every property. It was obscene..... now... zip. Zilch. Nada. RE agent was pretty narky when she visited today. Maybe rents will lower soon

Also, more news, one of my daughters clients, was hospitalised Thursday. Coma. Still in it. Outlook looks grim.


So, while I dont know someone with it, I know of people with it.

I might add, that the whole "business closing and social distancing" thing here is 100% crap. The main road here is busier than ever. Shops are doing a ripping trade. Tradies and deliveries have increased FIVE FOLD. They are going gang-busters on the building sites.

For the data fiends, the local government has built this dashboard: Microsoft Power BI

It has four parts.

Its not bad.

My area is "Molonglo" (Its a lovely area. visit some time )

Data sources are listed on page 4.

This ...thing... keeps getting worse.

Apologies to be so spammy tonight (SWMBO is sick and in bed, so Im a tad bored!).

https://www.biorxiv.org/content/bior...06213.full.pdf

and a preview of the info:

"In this study, we selected 95 strains of SARS-CoV-2, isolated from 11 different countries...The results obtained...indicate high severity of SARS- CoV-2 ...with inherent capability of unique mutations and the evolving viral replication strategies to adapt to human hosts."


Development of universal vaccines against the novel SARS-CoV-2 holds utmost urgency...However...the underlying severity hidden in the SARS-CoV2 genomes is required to be fully understood.

We revealed unique single nucleotide polymorphisms (SNPs)...within 10 viral isolates from USA. These ...[indicate] highly evolved strains of the novel SARS-CoV-2 circulating in the population of USA [more] than in other countries.

Furthermore, we found an isolate from USA...to carry frameshift mutation... Thus, we reason that the replicative machinery of the novel SARS-CoV-2 is fast evolving to evade host challenges and survival.

These mutations are needed to be considered, otherwise it will be difficult to develop effective treatment strategies.

...two proteins also...might confer selective advantage to the virus. Through the construction of SARS-CoV-2-human interactome, we further reveal multiple host proteins...which are manipulated...for mediating host immune mechanism for its survival.

In this study, we selected 95 strains of SARS-CoV-2, isolated from 11 different countries to understand the transmission patterns, evolution and pathogenesis of the virus.
The results obtained from the analyses indicate high severity of SARS- CoV-2 isolates with inherent capability of unique mutations and the evolving viral replication strategies to adapt to human hosts.

...two genes...found to...enhance the multiplication and facilitate growth of [the] virus inside the host.

Similarly, the S protein which helps in the entry of virus to the host cells...[was] found to be accelerated towards...the successful ability of enzyme to initiate the infection.
Another positive diversifying gene...protects the genetic material of virus from host immune responses...

Overall, the data represent that the growth and multiplication related genes are highly evolving.

Although the primary mode of infection is human to human transmission through close contact, which occurs via spraying of nasal droplets from the infected person, the primary site of infection and pathogenesis of SAR-CoV-2 is still not clear and under investigation.

The genomes of six isolates, specifically from USA, were found to harbour unique amino acid SNPs and showed amino acid substitutions in ORF1b protein and S-protein, while one of them also harboured a frameshift mutation. This is suggestive of the severity of the mutating viral genomes within the population of USA. These proteins are directly involved in formation of viral replication-transcription complexes (RTC).

Therefore, we argue that the novel SARS- CoV-2 has fast evolving replicative machinery and that it is urgent to consider these mutants in order to develop strategies for COVID19 treatment...these mutants...might confer selective advantage to evade host responsive mechanisms...It is predicted that major immune-pathogenicity mechanism by SARS-CoV-2 includes the host cell environment alteration by disintegration by signal transduction pathways and immunity evasion by several protection mechanisms. The mode of entry of this virus by S-proteins inside host cell is still unclear but it might be similar to SARS CoV-1 like viruses.

Lastly, we believe that COVID-19 is being transmitted from human to human, but as more data accumulate the picture will be more clear, as these virus spread beyond the imagination of scientific community.

At the White House briefing this morning (AEST) Trump really let rip on the press. The salient parts of it are covered in this article:
Wounded by media scrutiny, Trump turned a briefing into a presidential tantrum | US news | The Guardian

There are 3 short vids in there, and it's the first and last that the most relevant. The second one just shows the bizarre PR reel that he got his staff to put together.

Originally Posted by Tccp123

Well I still don't know anyone with the virus, nor do I know anyone who knows anyone with it! That's not surprising because here in Queensland only one in 20,000 people that you're likely to run into on the streets has it.

This ap, from our glorious government will probably send you into a full blown conniption!

It has a full time tracker built in

Just released....

Coronavirus Australia - Apps on Google Play

Originally Posted by Tccp123

Well I still don't know anyone with the virus, nor do I know anyone who knows anyone with it! ....

One of my friends died last week from Covid-19. In the UK.

Regards from Perth

Derek

So sorry to hear that mate.

Originally Posted by bueller

So sorry to hear that mate.

Thanks Dan.

I'm still out on the streets without a mask, sanitiser or the virus.

Kuffy, the problem is that there are those who have the virus but do not show symptoms. They will infect others, who will develop symptoms.

Regards from Perth

Derek

Originally Posted by FenceFurniture

Today's spreadsheet attached.

Similar to Bobl watching the Italian situation closely I have been reading the Dutch papers and news.

Today I found out that the Dutch statistics only cover the infection rate and death numbers of those tested for the virus, anyone dying that only saw a GP and not tested, was not counted.

Very few were tested because of lack of tests available so I do not trust the figures from Netherlands. I presume that is the same for a lot of countries.

Peter.